ABSTRACT
Abstract: The aim of this study was to evaluate the health-related quality of life (QOL) of patients with squamous cell carcinoma (SCC) according to tumor location. The sample consisted of 27 patients with primary SCC in the oral cavity (n = 15), pharynx (n = 7), and larynx (n = 5) who were undergoing cancer treatment at the Cancer Hospital of Londrina, regardless of age, sex, clinical stage, and type of antineoplastic treatment. Health-related QOL was evaluated using the 30-item Cancer-Quality of Life Questionnaire (QLQ-C30), the 35-item Head and Neck Cancer-Quality of Life Questionnaire (QLQ-HN35), and the University of Washington Quality of Life Questionnaire (UW-QOL). These questionnaires were administered individually to each patient before ambulatory care. Sociodemographic data (age and sex) and clinical data (T stage, tumor location, and type of antineoplastic treatment) were collected from the patients' medical records. Scores were compared according to tumor location using the chi-squared test and one-way analysis of variance (p < 0.05). No score differed significantly according to tumor location. It can be concluded that the health-related QOL of patients with SCC was not influenced by tumor location.
Subject(s)
Humans , Male , Female , Aged , Quality of Life , Mouth Neoplasms/pathology , Mouth Neoplasms/drug therapy , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/drug therapy , Pharyngeal Neoplasms/pathology , Pharyngeal Neoplasms/drug therapy , Laryngeal Neoplasms/pathology , Laryngeal Neoplasms/drug therapy , Sex Factors , Cross-Sectional Studies , Surveys and Questionnaires , Analysis of Variance , Age Factors , Middle Aged , Neoplasm Staging , Antineoplastic Agents/therapeutic useSubject(s)
Humans , Male , Adult , Pharyngeal Neoplasms/pathology , Sarcoma, Kaposi/pathology , Acquired Immunodeficiency Syndrome/complications , Antiretroviral Therapy, Highly Active , Pharyngeal Neoplasms/etiology , Pharyngeal Neoplasms/drug therapy , Sarcoma, Kaposi/etiology , Sarcoma, Kaposi/drug therapyABSTRACT
Se presentan dos casos clínicos de tumores parafaríngeos de niños tratados en el Servicio de ORL del Hospital Regional Valdivia. El primero corresponde a un coristoma que histológicamente constituye tejido neuroglial maduro el cual fue tratado con cirugía exclusiva. El segundo caso es un Rabdomiosarcoma embrionario que fue sometido a una resección con quimioterapia y radioterapia según protocolo y a una cirugía de rescate por una recidiva local. Se revisa la literatura con especial énfasis a la anatomía, técnica quirúgica e histología de los tumores que afectan el espacio parafaríngeo
Subject(s)
Humans , Female , Child, Preschool , Pharyngeal Neoplasms/diagnosis , Choristoma/diagnosis , Rhabdomyosarcoma, Embryonal/diagnosis , Tracheostomy , Pharyngeal Neoplasms/surgery , Pharyngeal Neoplasms/drug therapy , Pharyngeal Neoplasms/radiotherapy , Choristoma/surgery , Rhabdomyosarcoma, Embryonal/surgery , Neoplasm MetastasisABSTRACT
As afeccoes malignas das tres regioes da faringe - nasofaringe, orofaringe e hipofaringe - sao bastante distintas entre si no que diz respeito ao quadro clinico e ao tratamento. Enquanto na nasofaringe os tumores sao menos diferenciados e tratados principalmente pela radioterapia, os tumores da orofaringe e da hipofaringe sao mais diferenciados e, como regra, respondem melhor a terapeutica cirurgica associada a radioterapia pos-operatoria. Na terapeutica dos tumores da faringe, os linfonodos cervicais devem ser tratados pelo esvaziamento cervical e / ou pela radioterapia